Seminars are open to all visitors and start Monday at 16:00 sharp. Coffee and tea will be served from 15:45. The seminar series lectures are in a colloquiumzaal at the third floor (entrance level) of the Faculty building of Erasmus MC.
Silvia Arber
Assembling motor circuits for function
| 2010-02-01 | Room: Ae 406 |
The assembly of neuronal circuits depends critically on genetic programs specifying neuronal subpopulations during development and allowing them to form synapses with appropriate target cells. A unique property of circuits involved in motor control is that they allow making a direct link between fine details of dedicated circuits and an immediate behavioral output. This property makes them well-suited for studies aimed at understanding how neuronal circuits control a defined function in the nervous system. The coordinated and sequential developmental assembly of local spinal circuits and neuronal pathways feeding into the spinal cord provides the foundation for the control of motor behavior in the adult and represents the main focus of our work. This talk will present our recent progress in understanding genetic pathways and cellular mechanisms involved in controlling the assembly of motor circuits in the spinal cord.