Seminars are open to all visitors and start Monday at 16:00 sharp. Coffee and tea will be served from 15:45. The seminar series lectures are in a colloquiumzaal at the third floor (entrance level) of the Faculty building of Erasmus MC.
Tom Mrsic-Flogel
Two-photon calcium imaging of network activity in mouse visual cortex
| 2010-04-12 | Room: Ae 406 |
The majority of our knowledge about how the brain represents sensory information has been obtained from recordings of one or few neurons at a time or from global mapping methods such as fMRI. These approaches have left unexplored how neuronal activity is distributed in space and time within a cortical column and how hundreds of neurons interact to process sensory information. Recent methodological advances now enable the simultaneous and largely unbiased sampling of neuronal activity from dozens of neurons in the neocortex by means of in vivo two-photon calcium imaging. We use this approach in the mouse visual cortex to characterize the detailed functional organization of a cortical column and investigate how neuronal subsets within a local cortical network respond to visual stimuli. Host G. Borst